Invasive measurements |
Remifentanil |
Sufentanil |
Δ-values (After – Before) |
Before |
After |
p-value |
Before |
After |
p-value |
Remifentanil |
Sufentanil |
p-value |
Cardiac Index (L/m2/minute) |
3.5 ± 0.8 |
3.2 ± 0.6 |
0.137#) |
3.2 ± 0.8 |
3.2 ± 0.8 |
0.900#) |
-0.34 ± 0.80 |
0.01 ± 0.50 |
0.180!) |
Heart rate (beats/minute) |
72 ± 8 |
69 ± 10 |
0.151#) |
69 ± 9 |
66 ± 13 |
0.166#) |
-3.1 ± 7.7 |
-2.9 ± 7.0 |
0.930!) |
Mean Arterial Pressure (mmHg) |
104 ± 13 |
91 ± 15 |
0.001#) |
107 ± 21 |
94 ± 24 |
0.003#) |
-12.8 ± 11.5 |
-13.1 ± 12.4 |
0.933!) |
Central venous pressure (mmHg) |
6 ± 7 |
7 ± 7 |
0.366#) |
7 ± 7 |
10 ± 6 |
0.022#) |
1.5 ± 6.3 |
2.7 ± 3.7 |
0.572!) |
Pulmonary artery Pressure (mmHg) |
17 ± 4 |
21 ± 7 |
0.020#) |
19 ± 9 |
23 ± 9 |
0.036#) |
3.7 ± 5.3 |
3.9 ± 6.0 |
0.927!) |
Central venous oxygenation (%) |
74 ± 6 |
77 ± 9 |
0.221#) |
76 ± 4 |
74 ± 8 |
0.436#) |
2.6 ± 7.4 |
-1.9 ± 8.6 |
0.155!) |
Peripheral saturation (%) |
97 ± 3 |
98 ± 3 |
0.236#) |
98 ± 3 |
97 ± 4 |
0.827#) |
1.2 ± 3.5 |
-0.3 ± 4.6 |
0.372!) |
Stroke volume Index (ml/m2/beat) |
48.8 ± 13.3 |
45.6 ± 7.9 |
0.399#) |
46.4 ± 13.2 |
49.4 ± 13.3 |
0.240#) |
-3.1 ± 13.5 |
3.0 ± 8.7 |
0.176!) |
Echocardiographic measurements |
|
|
|
|
|
|
|
|
|
Global longitudinal peak systolic strain (%) |
-16 (-18 - -13) |
-16 (-18 - -15) |
0.068*) |
-14 (-17 - -13) |
-15 (-16 – 15) |
0.492*) |
-1.9 (-4.0 - 0.7) |
-1.3 (-3.1 - 1.3) |
0.697&) |
S-max (average lateral and medial) |
9.2 ± 2.0 |
9.6 ± 2.4 |
0.307#) |
8.8 ± 1.5 |
8.7 ± 1.9 |
0.705#) |
0.5 ± 1.6 |
-0.1 ± 0.8 |
0.150 !) |
E/E' ratio (average medial/lateral) |
9.0 (6.5 – 10.6) |
8.0 (6.0 – 9.4) |
0.502*) |
7.3 (6.3 – 8.2) |
8.3 (6.4 – 10.5) |
0.557*) |
0.8 (-2.5 - 1.0) |
-1.0 (-1.7 - 2.7) |
0.447&) |
E’/A’ ratio (average medial/lateral) |
0.8 (0.7 – 0.9) |
0.8 (0.7 – 1.0) |
0.685*) |
0.9 (0.8 – 1.0) |
0.8 (0.6 – 1.0) |
0.922*) |
0.1 (-0.1 - 0.1) |
0.0 (-0.2 - 0.1) |
0.687&) |
E’ – TD early diastolic velocity (cm/s) |
9.2 ± 1.6 |
9.9 ± 1.6 |
0.164#) |
10.1 ± 1.7 |
10.0 ± 2.2 |
0.834#) |
-0.7 ± 1.5 |
0.1 ± 1.5 |
0.244 !) |
A’ – TD atrial diastolic velocity (cm/s) |
11.3 ± 2.3 |
12.3 ± 3.4 |
0.226#) |
11.3 ± 1.8 |
11.6 ± 2.8 |
0.824#) |
-1.0 ± 2.8 |
-0.2 ± 2.2 |
0.432 !) |