Preoperative measurement (baseline) Mean (SD) Day of operation Mean (SD) POD 1 Mean (SD) POD 2 Mean (SD) POD 3 Mean (SD) POD 4 Mean (SD) POD 5 Mean (SD)
Diuresis l/day
Placebo
Nutrition

1.9 (1.0)
1.8 (1.1)

2.2 (0.9)
2.4 (1.1)

1.9 (1.0)
1.9 (1.0)

2.8 (1.2)
2.4 (1.2)

2.3 (1.0)
1.7 (1.0)

1.9 (1.3)
1.5 (1.1)

1.7 (1.0)
1.4 (0.9)
U-creatinine mmol/day
Placebo
Nutrition

5.8 (3.4)
6.2 (3.0)

5.1 (2.2)
5.2 (3.0)

7.7 (5.6)
7.7 (5.1)

4.4 (2.7)
5.9 (5.0)

5.8 (3.9)
7.5 (4.4)

5.8 (4.3)
9.4 (6.5)

7.3 (3.7)
10.9 (8.8)
S-creatinine* mmol/l
Placebo
Nutrition

0.080 (0.018)
0.085 (0.021)

0.071 (0.019)
0.072 (0.019)

0.080 (0.021)
0.084 (0.025)

0.076 (0.018)
0.083 (0.028)

0.078 (0.021)
0.081 (0.029)

0.087 (0.023)
0.082 (0.031)

0.091 (0.026)
0.087 (0.025)
Weight change Kg
Placebo
Nutrition
   
1.22 (1.68)
2.09 (1.91)

1.26 (1.66)
1.93 (2.17)

0.48 (1.53)
1.16 (1.53)

- 0.98 (1.58)
0.26 (2.18)

-1.62 (2.12)
-0.33 (2.06)
Weight change Percent (%)
Placebo
Nutrition
   
1.55 (2.29)
3.01 (2.40)

1.65 (2.15)
2.83 (3.45)

0.62 (2.27)
1.82 (2.46)

-1.30 (2.40)
0.64 (3.67)

-2.05 (2.70)
-0.20 (3.05)
Deficit kg/day
Placebo
Nutrition
 
4.95 (1.95)
4.97 (2.55)

1.79 (1.67)
1.75 (1.46)

0.82 (1.14)
0.78 (1.38)

0.45 (1.13)
1.01 (1.21)

-0.03 (1.45)
0.60 (1.67)

-0.50 (1.62)
-0.35 (1.71)
Weight change compared to preoperative weight. Deficit: total input (intravenous supply, product and oral water) minus diuresis
*p<0.05 (repeated measures multivariate test (Pillai’s trace)) p<0.05 comparison between groups (univariate F test)
Table 3: Diuresis and weight charges.