Biomarkers of oxidative stress |
ROS and RNS |
SOD radical, H2O2, NO, HOCL, peroxides, peroxyl radical, peroxynitrite, metal-oxo complexe, semiquinone radical, heme
proteins, singlet oxygen; |
Products of lipid peroxidation |
MDA, 4-HNE, hydroperoxides, conjugated dienes, F2-isoprostanes dicarboxylic acids; |
Products of DNA oxidation |
Modified bases, 8-oxo-2' deoxyguanosine, strand breaks; |
Primary products of protein oxidation |
o-tyrosine, o,o.-dityrosine, 3 chlorotyrosine,3-nitrotyrosine, dihydroxyphenylalanine, protein disulfides,
methionine sulfoxide,
hydroperoxides of isoleucine, leucine, valine, protein carbonyls adipic semialdehyde,
2-oxohistidine; |
Secondary products of protein
oxidation |
AGEs, ALEs, EAGLEs, Pentosidine, MDA-Lys, MDA-LDL, CML, CMA, CEL, Crosslines HNE (Lys, His, Cys) Argpyrimidine,
Vesperlysines, Pyrroles, GOLD, MOLD; |
Antioxidant defense systems and
total antioxidant status |
Levels of enzymes and antioxidants; |
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