Figure 11: The effects of imeglimin (0.1 mmol·L-1 or 1 mmol·L-1) on protection of rat pancreatic β cells against apoptosis were investigated as described in Methods. Values are mean (SEM) of n = 4 in each group. Imeglimin provided significant protection against apoptosis in the presence of cytokines controls: § P<0.05 and §§§ P<0.001 for between group comparisons as indicated on the graph; ***P<0.001 compared with control plus cytokines; ### P<0.001 compared with control minus cytokines.