| Variable
(units) |
pGDM-P
n=29 |
pGDM-N
n=56 |
pNGT
N=40 |
p-values |
| Age (years) |
31.50
(27.50 - 35.50) |
30.00
(26.00 - 35.00) |
27.00
(25.00 - 35.50) |
0.1145 |
| BMI (kg/m2) |
25.12
(21.83 - 29.04)b |
24.44
(21.26 - 27.22)a |
22.00
(20.31 - 24.33) |
0.0022 |
| Waist circumference (cm) |
80.00
(73.00 - 96.00)b |
82.00
(73.00 - 90.00)a |
74.50
(69.00 -78.00) |
0.0010 |
| Fasting plasma glucose(mmol/l) |
5.16
(4.77 - 5.88)b,c |
4.77
(4.44 - 5.13) |
4.72
(4.50 - 4.78) |
0.0002 |
| 2-h (OGTT) plasma glucose (mmol/l) |
8.27
(8.05 - 8.77)b,c |
5.88
(5.44 - 6.66)a |
4.84
(4.77 - 5.44) |
<0.0001 |
| Insulin (pmol/l) |
57.44
(42.36 - 95.84)cc |
54.17
(41.67 - 69.45) |
63.20
(54.87 - 71.53) |
0.0353 |
| sVCAM-1 (ng/ml) |
960.30
(353.73 - 1638.03) |
1127.63
(466.68 - 1582.58)a |
672.05
(455.70 - 1113.46) |
0.0553 |
| sICAM-1 (ng/ml) |
295.90
(238.80 - 363.38)b |
299.28
(243.46 - 364.19)a |
140.40
(121.34 - 179.90) |
<0.0001 |
| sE-selectin (ng/ml) |
35.80
(26.37 - 43.65)b |
28.57
(20.35 - 42.54)a |
20.90
(17.11 - 26.01) |
0.0022 |
| tPA:Ag (ng/ml) |
6.01
(4.09 - 7.51)b |
4.68
(3.25 - 7.24)a |
3.50
(2.66 - 4.64) |
0.0005 |
| vWF:Ag (%) |
107.79
(96.20 - 131.59) |
104.30
(95.36 - 117.22) |
104.87
(74.96 - 125.67) |
0.6498 |
| PAI-1:Ag (ng/ml) |
57.67
(49.44 - 83.75) |
57.09
(42.85 - 85.12) |
71.36
(50.54 - 81.80) |
0.2178 |
| hsCRP (µg/ml) |
1.30
(0.81 - 2.86)b |
1.32
(0.66 - 2.76)a |
0.41
(0.22 - 0.79) |
<0.0001 |
| Total-cholesterol (mmol/l) |
5.33
(4.84 - 5.92)b |
5.02
(4.50 - 5.48)a |
4.56
(4.27 - 5.09) |
0.0022 |
| HDL- cholesterol (mmol/l) |
1.45
(1.29 - 1.73)b |
1.55
(1.27 - 1.73)a |
1.73
(1.56 - 1.82) |
0.0048 |
| LDL- cholesterol (mmol/l) |
3.26
(2.97 - 4.06)b |
3.03
(2.77 - 3.54)a |
2.57
(2.30 - 3.05) |
<0.0001 |
| Triglyceride (mmol/l) |
1.21
(1.02 - 2.22)b,c |
79.00
(63.00 - 116.00) |
74.50
(58.50 - 91.00) |
0.0004 |
| Triglyceride/ HDL cholesterol |
1.83
(1.35 - 4.06)b,c |
1.33
(0.95 - 2.30) |
1.11
(0.89 - 1.50) |
0.0003 |
| HOMA-IR (mmol/l) |
2.32
(1.27 - 3.49)ccc |
1.64
(1.22 - 2.15) |
1.89
(1.58 - 2.37) |
0.0499 |
P-values for testing over the three groups (ANOVA): a-p<0.05 controls versus previous GDM with normal glucose regulation; b-p<0.05 controls versus previous GDM with
pre-diabetic state; c-p<0.05 previous GDM with normal glucose status versus previous GDM with prediabetic state, cc-p=0,05, ccc-p=0,06 |
