Values are mean + SEM. (n=5 per group). bP<0.05 significantly different from the control, abP<0.05 significantly different from the group treated with only levcromakalim. C: Control (normal saline group) Lev: potassium channel activated group LevG: potassium channel activated group treated with glibenclamide LevM: potassium channel activated group treated with metformin LevI: potassium channel activated group treated with insulin LevI10 : all died

Figure 1: The effect of levcromakalim treatment on the creatinine clearance of normal Wistar albino rats treated with glibenclamide, metformin and insulin.