Figure 1: Calculation of DySF through Transition Density Profiles. Patient
input glucose data, illustrating the 40 mg/dL increments in alternating grey and
white. A) B) Smoothed input data in bins.C) Blow-up of data in (B) highlighting the
monotonic changes to be recorded in theD) Transition Density Profile which
compiles monotonic changes that occur in a specific time interval. The shaded
region shows all the monotonic transitions that occurred in less than 1 h. DySF
is calculated as the sum of the number of transitions greater than one, weighted
by the magnitude of the transition. (Example above: DySF = 0.3*|-7| + 0.3*|-3| +
2.6*|-2| + 1.75*|2| + 0.9*|3| + 0.9*|4| + 0.3 *|5| = 19.5. The weights listed as 0.3
and 2.6 for example are determined by the number of actual transitions occurred
divided by the length of time the sample set is measured. Since there was one
transition of -7 bins that occurred during the 5000 minutes or 3.4 days measured,
we get 1/3.4 = 0.3 to be our weighted factor for this transition.) |