No Nephropathy

Nephropathy

Undetermined

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

Death from renal causes

 

 

 

 

 

 

   Crude

4.38 (0.46-42.07)

0.201

0.50 (0.27-0.93)

0.027

0.97 (0.40-2.33)

0.938

   Adjusted  for PSa

NCb

-

0.49 (0.25-0.95)

0.034

0.83 (0.33-2.09)

0.688

Death from other causes

 

 

 

 

 

   Crude

0.65 (0.43-0.98)

0.041

0.73 (0.57-0.93)

0.011

1.27 (1.01-1.60)

0.039

   Adjusted  for PSa

0.58 (0.37-0.91)

0.018

0.73 (0.56-0.95)

0.019

1.26 (0.97-1.63)

0.085

Death from all causes

 

 

 

 

 

 

   Crude

0.70 (0.47-1.04)

0.081

0.68 (0.55-0.87)

0.001

1.25 (1.01-1.56)

0.048

   Adjusted  for PSa

0.65 (0.42-0.99)

0.049

0.69 (0.54-0.88)

0.003

1.22 (0.95-1.56)

0.122

aPS: Propensity Score (age, sex, duration of diabetes, systolic blood pressure, diastolic blood pressure, HbA1C, total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, creatinine, history of ischemic heart disease, smoking, alcohol drinking, use of insulin, antihyperglycemic drugs, antihypertensive drug and antidyslipidemic drugs) bNC: Non-calculable due to small number of events
Table 3: Hazard ratio (HR) and 95% confidence interval (CI) for death from renal causes, other causes and all causes in patients prescribed with ACEIs/ARBs, classified by nephropathy status at registration.