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Figure 1: Resistin inhibits insulin-stimulated 2-DOG uptake in 3T3-L1 adipocytes. 3T3-L1 adipocytes were transduced with Ad-resistin or Ad-lacZ. At 48 hrs after infection, serum-starved 3T3-L1 adipocytes were treated with insulin (100 ng/mL), followed by measurement of 2-DOG uptake. Data represent the mean ± SE of 3 independent experiments (each experiment was performed with 6 samples). *P < 0.05. |