S. No Variables*(Normal range)         Control Group    Thiamine allocated group Placebo allocated group
1 Age (years) 49.13±8.79 52.7± 8.4 52.40± 8.7
2 Sex 11F,9M 9M, 11F 7M, 13F
3 Height (m) 1.59±0.7 1.57± 28.4 1.58± 52.9
4 Weight (kg) 68.56± 16.99 69.12± 18.4 71.27± 22.7
5 Diastolic  BP (mmHg) (<90) 78± 7 87 ± 8 84 ± 6
6 Systolic BP (mmHg) (<140) 118.2±9 126 ± 14 131 ± 10
7 BMI(kg/m2)(19-40) 26.93± 4.92 28.1 ± 4.6 28.3 ± 4.4
8 FBS (mg/dl) (<100) 89.3±19.64 181.8.±57.6C 171±55.8C
9 HbA1c (%)(4.3-6.1) 5.6±0.39 9.2±1.3 B 8.82±.1.8 B
10 LDL (mg/dl)(70-130) 115.89±29.37 106.34±47.14 106.34±35.96
11 VLDL (mg/dl)(5-41) 26.62±20.22 46.33±31.79 A 42.67±7.103 A
12 HDL (mg/dl)(35-60) 44.15±120.05 49.88±13.53 A 47.95±10.44 A
13 Cholesterol (mg/dl)(0-200) 187.21±33.19 203.40±50.27 B 185.22±40.98
14 TG (mg/dl)(30-150) 133.10±108.45 240.10±168.55C 156.15±81.740 B
15 GFR (ml/min)(90-120) 102.43±38.60 85±19 93±23
16 Uric acid mg/dl(3.5-8.5) 4.65±1.00 4.65±.10.05 3.99±1.09
17 BUNmg/dl(7-21) 10.45±2.350 11.37±4.87 12.25±2.245 A
18 Serum Creatinine mg/dl(0.8-1.4) 0.820±.132 0.915±0.195. 0.84±0.24 A
19 Urine Creatininemg/dl(30-125) 47.63±36.117 42.39±25.635 A 42.67±31.76 A
20 Bilirubin (mg/dl ) (0.1-1) 0.59±0.403 0.55±.244 0.52±0.279
21 ALP (U/L) (20-160) 95.90±34.20 103.30±33.4847 A 88.20±29.848 A
22 AST (U/L) (15-37) 29.15±11.123 22.60±9.703 21.65 ±7.700A
23 ALT (U/L) (30-65) 40.90±12.191 360.05±10.49 A 36.10±10.40
24 CK(U/L)( M:38-174,F:96-140) 108.50±70.04 81.85±52.30 69.95±55.35
25 Plasma thiamine (nmol/L) 44.63-93.7 10.6(0.8-84.5) C 7.1(1.1-31.3) C
26 Urine Albumin (mg/24h)(0-30) 7.968±5.07 53.86±22.62 C 55.74±23.71 C
27 Urine thiamine (µmol/24 h)   1.63(0.45-7.66) C 1.53(0.67-4.46) C
28 PAI1(ng/ml) (7-43) 3.094±1.83 5.40±1.01C 5.91±1.68 C
29 Protein kinase C(pg/ug) 20.57±7.7 68.00±15.30C 76.65±56.22C
30 Plasma thiols(nmol/µl) 5.13±0.85 3.91±.72B 4.15±0.86B
Table 1: Average values of the various physical and biochemical parameters of the different groups at baseline (n=20).