Enzyme |
Gene accession numbers from ToxoDataBase a |
Glucosephosphate-Mutase I (GPM1) |
76.m00002 |
Glucosephosphate-Mutase II (GPM2) |
641.m00009 |
Fructose-Biphosphatase I (FBP1) |
20.m03907 |
Fructose-Biphosphatase II (FBP2) |
50.m00005 |
PEP-Carboxykinase I (PEP-CK1) |
80.m00002 |
PEP-Carboxykinase II (PEP-CK2) |
80.m02252 |
Pyruvate-Carboxylase (Pyc) |
76.m01567 |
In contrast to most of the other T. gondii gluconeogenesis genes,namely fructose-biphosphatase,glucosophosphate-mutase and PEP-carboxykinase, which are
encoded twice in the genome,pyruvate-carboxylase is only encoded once and the enzyme is localized inside the single mitochondrion,while the remaining reactions of
gluconeogenesis are typically cytosolic [365]. a(www.toxodb.org/toxo/home.jsp) |