Protein name |
Gene name |
Change in expression |
Microarray experiment |
6-Phosphogluconolactonase |
PGLS |
↓ |
↓ |
Acetyl coenzyme A acyltransferase |
ACAT1 |
M |
↑ |
Adenylate kinase 2 isoform a |
AK2 |
↑ |
↑ |
Adenylate dehydrogenase 1A3 |
ALDH1A3 |
↑ |
↓ |
Aldehyde dehydrogenase X |
ALDH1B1 |
↓ |
↓ |
Aldose reductase |
AKR1B1 |
↑ |
↑ |
Carbonyl reductasea |
CBR1 |
↓ |
|
Cathepsin B |
CTSD |
↓ |
↓ |
Coproporphyrinogen oxidase |
CPOX |
↑ |
|
Glutathione synthetase |
GSS |
↑ |
|
Glutathione-S-transferasea chain A |
GSTA2 |
↓ |
↓ |
Phosphoenolpyruvate carboxykinase |
pck1 |
↓ |
|
Protein-L-isoaspartate O-methyltransferase |
PCMT1 |
↑ |
|
Pyridoxine 5’-phosphate oxidase |
PNPO |
↓ |
|
Pyrophosphatase (inorganic) |
PPA1 |
↓ |
|
Host cell proteins were designated as being down regulated in expression (↓), upregulated (↑), or modulated (M). Modulated proteins had expression altered across
several isoforms on the same gel using the Amersham difference gel electrophoresis, and this probably indicated a posttranslational modification event [354].