Figure 6: Kinetics of CD25 expression of non-regulatory and regulatory T cells of cells activated in the absence and presence of costimulation blockade.
CD25 was evaluated on sequential divisions of FoxP- and FoxP3+ CD3+CD4+ T cells stimulated in the absence or presence of costimulation blockade and histograms are shown (A). CD25 expression was assessed of on FoxP3- and FoxP3+ subpopulations of freshly isolated (day 0) and following 1 day of culture and 3 days of culture according to divisional generation (Div Gen) assessed by CFSE under the conditions shown. Shown are results from one of 3 independent experiments.