Baseline   3 months 6 months
Variable N Mean ± SD N** Mean (CI) p-value* Mean (CI) p-value*
Age (years) 33 42.7 ± 12.3          
Height (cm) 33 172 ± 1.0          
Weight (kg) 33 118.1 ± 23.8 32 -8.7 (-10.6 to -6.7) <0.001 -11.1 (-13.5 to -8.6) <0.001
BMI (kg/m2) 33 40.0 ± 7.3 32 -2.9 (-3.6 to -2.3) <0.001 -3.8 (-4.6 to -2.9) <0.001
WC (cm) 33 124 ± 15.6 32 -6.5 (-7.8 to -5.1) <0.001 -10.8 (-12.7 to -8.9) <0.001
Body fat (%) 31 46.7 ± 6.8 29 -4.3 (-5.3 to -3.3) <0.001 -4.7 (-5.9 to -3.5) <0.001
Fat mass (kg) 31 54.1 ± 12.6 29 -8.8 (-10.5 to -7.1) <0.001 -10.2 (-12.3 to -8.1) <0.001
Fasting glucose (mmol/L) 33 5.0 ± 0.9 31 -0.1 (-0.5 to 0.3) 0.648 0.6 (0.3 to 0.8) <0.001
2h glucose (mmol/L) 33 8.2 ± 3.0 31 -1.2 (-2.2 to 0.2) 0.017 -0.8 (-1.5 to 0.0) 0.042
SE (%) 33 81.8 ± 6.9 27 -1.7 (-3.3 to -0.1) 0.035 -1.5 (-3.3 to 0.3) 0.095
ESS 33 3.4 ± 2.7 32 -0.3 (-0.8 to 0.3) 0.337 -0.5 (-1.1 to 0.1) 0.078
PA (min/day) 33 69 ± 49 27 30 (7 to 53) 0.011 9 (-8 to 26) 0.273
*Analysis by repeated measures ANOVA
**Number of subjects that had baseline, 3 and 6 months measurements for the analyzed variables in the repeated measures ANOVA
Table 1: Baseline characteristics and changes from baseline after 3 and 6 months of treatment (mean (CI, confidence interval)).