Age of diagnosis seems to be confined to adulthood.
Presence of HLA-DR3/DR4 and HLA-DR2 is low-moderate.
Anti-GAD65 is the marker of choice, but IA-IA2 antibodies can also be detected.
Plasma insulin is usually low with absent ketosis.
Insulin resistance presence is variable, and it´s considered a major role in the pathogenesis.
Diagnosis of Metabolic Syndrome is variable.
Body Mass Index is normal or high.
Initial treatment suggested is insulin, along with oral antihyperglycemic agents such as Metformin or Thiazolidinediones when appropiate.
Table 1: Factors associated with LADA.