Haplotype Case Control Ca-Freq Co-Freq Ca-D' Ca-r2 Co-D' Co-r2 Odds-R 95%Lo 95%Hi Pc
TACCACG 181 244 22.9% 30.8% 0.8825 0.03714 0.9021 0.04237 1 1 1  
TGCCACA 64 78 8% 9.8% -0.009883 7.75e-5 -0.03606 0.001167 1.11 0.76 1.62  
TACCGCA 59 108 7.4% 13.6% 1 0.01344 1 0.01829 0.74 0.51 1.07  
TACCATA 52 80 6.5% 10.1% 1 0.01227 1 0.01291 0.88 0.59 1.31  
CGCCGCA 41 34 5.2% 4.3% 1 0.4007 1 0.384 1.63 1.00 2.67  
TGCCATG 41 33 5.2% 4.2% -0.02038 0.000205 0.5242 0.001439 1.68 1.03 2.76  
TACCGCG 31 6 3.9% 0.76% 1       0.01066 1       0.000914 6.28 2.62 15.06 0.00003
TACCACA 22 28 2.8% 3.5% -0.002983 2.422e-6 0.6362 0.001765 1.09 0.61 1.95  
TACCATG 21 5 2.7% 0.6% 1 0.004763 1 0.0007987 4.65 1.84 11.76 0.004
TGCCGCG 19 17 2.4% 2.1% -0.1551 0.005829 0.179 8.718e-5 1.50 0.76 2.95  
TACTGTG 19 1 2.4% 0.13% 1 0.004202 1 9.68e-5 15.76 2.44 101.70 0.00007
TATCACA 16 29 2% 3.7% 1 0.003412 1 0.00432 0.76 0.40 1.43  
TACTGCA 14 0 1.8% 0% 1       0.003412 1 0.00432 16.04 1.61 159.83 0.0007
CGCCGTG 13 20 1.6% 2.5% 1 0.005063 1 0.004677 0.87 0.43 1.79  
TACCGTA 12 2 1.5% 0.25% 1 0.1223 0.7455 0.1629 6.99 1.56 31.37 0.02
TATCATG 11 15 1.4% 1.9% 1 0.002475 1 0.002209 1.03 0.47 2.26  
TATCATA 10 2 1.3% 0.25% 1 0.002279 1 0.0002206 5.82 1.29 26.19  
CGCCACA 10 12 1.3% 1.5% 0.009883 7.75e-5 0.03606 0.001167 1.10 0.47 2.58  
TACTACA 10 31 1.3% 3.9% 1 0.0025315 1 0.002338 0.46 0.22 0.96  
TGCCGTA 9 5 1.1% 0.6% 1 0.001878 1 0.000662 2.32 0.77 7.04  
CGTCGTG 7 7 0.9% 0.9% 0.6348 0.0373 0.7977 0.05621 1.36 0.47 3.92  
TACCGTG 7 5 0.9% 0.5% 1 0.00137 1 0.0007303 1.73 0.56 5.34  
TACTATG 0 13 0% 1.6% 1 5.987e-13 1 0.001956 0.10 0.01 1.61 0.05
Other 123 17 15.5% 2.1% ------- -------- -------- ------ ----- ------ ------ --------
The table shows counts and percentages of estimated haplotypes. P-values (Pc) are corrected for 23 haplotype comparisons. Odds Ratio (OR) and corresponding 95% confidence intervals are given, whereas Global D’ for cases and controls are 0.7182 and 0.7922, respectively
Table 7: Haplotypes of seven CTLA-4SNPs in the Egyptian T1D and control samples.