Figure 6: Active site prediction of receptors against with its suitable ligands, A- active site prediction of MTr with respect to Agomelatine drug and luzindol, Bactive site prediction of IP3R with respect to 2-APB drug and IP3, C-active site prediction of SERCA with respect to thapsigargin drug, D- active site prediction of ORAI1 domain of CRAC with respect to STIM1 protein [17].