Figure 8: A biological network formed by 4 DEGs (colored) identified between the DM with albuminuria vs. N & Pre-DM monkeys without albuminuria and other related genes and protein complexes (gray). Three genes (HAVCR1, MMP7, and SPP1) labeled in green have higher expression and 1 gene (LCT) labeled in red has lower expression pattern in the DM monkeys with albuminuriathan those without (N &Pre-DM).Solid lines refer to direct interactions and dashed lines indirect interactions between proteins. Genes participating in 5 renal diseases are noted as Fx in yellow. All relationships are experimentally validated reported in literatures.