Transporter Location Transporter kinetics Reference
PMAT Intestine Km= 1.32 mM [13]
OCT1 Liver Km=1.47mM
Vmax =396pmol/min/mg protein
OCT2 Kidney Km=0.99mM,
Vmax =1444pmol/min/mg protein
MATE1 Liver and Kidney Km= 0.78mM,
Vmax = 4.46nmol/min/mg protein
MATE-K2 Kidney Km= 1.98mM,
Vmax = 1.69nmol/min/mg protein
Table 2: Inputs parameters used in control and post gastric bypass in the
transporter window of GastroPlusTM.