Figure 5: CPT1b deficiency does not alter whole body energy balance under a HFD condition In vivo whole body metabolism was assessed at 22 weeks of HFD feeding using comprehensive Lab Animal Monitoring System (CLAMS) with the average of the last 3 days (A-D), n=5-6. (A) Respiratory exchange rate (RER). (B) Energy expenditure. (C) Activity. (D) Food intake. Indirect calorimeter analysis (E-G), n=3-5. (E) Energy expenditure. (F) Respiratory exchange rate (RER). (G) Correlation between body weights change and RER. (H) Rectal temperature. n=4-5, *p<0.05.