Figure 3: Insulin tolerance test in C57BL/6 and S6K2-/- mice.

A, ITTs were performed on the mice described in the legend to Fig. 1. Groups (n=15) of mice indicated were fasted for 6 h before being injected intraperitoneally with insulin (0.75 U/kg). Blood glucose levels were measured prior to insulin injection (time zero) and 30, 60 and 120 min following insulin administration. B, Area under the Curve (AUC) measurements performed on groups shown in A. ***P<0.001.