*significant difference versus baseline.
Figure 1: Effect of metformin on body mass index. BMI 32.3 ± 5.2 kg/m2 significantly reduced at 6 month 29.9 ± 4.8 kg/m2 (p=0.012), at 9 month 29.0 ± 4.8 kg/m2 (p=0.001) and at 1 year 28.4 ± 5.0 kg/m2 (p<0.001); BMI= body mass index.