Figure 1: Optical microscopy of diabetic (DM) and normal (NL) rat kidneys. Kidneys from normal and diabetic rats (30 days of DM) were stained in hematoxylin and eosin. Low magnification images (bars = 100 μm) show cortical region with convoluted tubules (arrows) and glomeruli (*). In DM higher magnification images (bars = 20 μm), it is possible to evidence proximal tubules with thinner walls (arrows) and reduced brush borders (arrow heads). No changes were observed in glomeruli.