Figure 8: Role of Altered Gene Function in Treg Apoptosis. Changes in the selected genes (Pla2g1b, Clps, and Pnliprp1) result in altered rates of Triglyceride hydrolysis, impacting the numbers of produced of free fatty acids. Altered fatty acid amounts then may affect a cell’s membrane, where changes in cell signaling processes via altered receptor molecules may result in Treg apoptosis.