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Figure 3: Increased acellular capillaries in Akita/+; TSP1-/- male mice. Trypsin digest of retinas from 7 month old wild-type, Akita/+ and Akita/+; TSP1-/- male mice were prepared and the number of acellular capillaries per retina were quantified (scale bar=50 μM). Arrow heads point to acellular capillaries. Please note more acellular capillaries in retinas from Akita/+; TSP1-/- male mice compared to either wild-type or Akita/+ male mice (*p<0.05: n ≥ 5 mice). |