Kappa value (p-value) Agreement
Topographic Edema Map (HRT III) vs Edema Index (HRT III)    
Mild DME 0.427(<0.001) moderate
Moderate DME 0.428(<0.001) moderate
Severe DME 0.424(<0.001) moderate
All DME 0.455(<0.001) moderate
Topographic Edema Map (OCT) vs Macular Thickness Value (OCT)    
Mild DME 0.473(<0.001) moderate
Moderate DME 0.437(<0.001) moderate
Severe DME 0.489(<0.001) moderate
All DME 0.497(<0.001) moderate
Topographic Edema Map (HRT III) vs Topographic Edema Map (OCT)    
Mild DME 0.542 (<0.001) Moderate
Moderate DME 0.427 (<0.001) Moderate
Severe DME 0.441 (<0.001) Moderate
All DME 0.485 (<0.001) Moderate
Edema Index (HRT III) vs Macular Thickness Value (OCT)    
Mild DME 0.099 (0.207) Slight
Moderate DME 0.199 (<0.001) Slight
Severe DME 0.319 (<0.001) Fair
All DME 0.252 (<0.001) Fair
p value<0.05 is significant
McNemar statistical test
Table 5: Agreement of edema status between HRT III and OCT to detect macular edema.