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Figure 2: The effect of captopril (cap) treatment (40 mg/kg and 80 mg/kg) on mean arterial blood pressure (BP) of diabetic and non-diabetic Wistar Kayoto (WKY) rats. The BP was increased (P<0.01) in diabetic rats compared to non-diabetic rats. The cap-treated (40 and 80 mg/kg) diabetic and nondiabetic rats showed a significant ( p<0.001) reduction in BP compared to their respective non treated control (cont) rats. Each column (n=7) represents meaną SEM. [57]. |