Figure 1: The regulation of surface DPP4 High glucose (30 mM) exposure for 48 h down regulates DPP4 expression on HK2 cells however there was no change at 24 h and 72 h. HK2 cells were labeled with DPP4-PE antibody and the percentage of DPP4 positive cells were measured with flow cytometry. N=3, *p<0.05