Coffee consumption (cups/day) No. of individuals No. of cases Adjusted RR (log value) 95% CI

Bidel et al., [2]

0-2 644 35 1.00 ( 0.000) Reference
3-4 1,041 54 0.79 (-0.236) (0.51, 1.22)
5-6 1,356 69 0.66 (-0.416) (0.43, 1.03)
≥ 7 796 52 0.94 (-0.062) (0.58, 1.52)

Grobbee et al. [3]

None 7,592 8 1.00 ( 0.000) Reference
≤ 1 13,048 23 0.58 (-0.545) (0.25, 1.36)
2-3 16,009 18 0.68 (-0.386) (0.36, 1.31)
≥ 4 8,940 5 0.48 (-0.734) (0.18, 1.31)
Table 2: Characteristics of two studies of coffee consumption and stroke that were included in a meta-analysis [4].