Number of variants Alpha MAF     0.01 0.05 100 0.05 0.05041 0.04712 100 0.01 0.01025 0.0098 100 0.001 0.00107 0.00114

Table 1: Type one error for the outlined approach (100 simulated variants, upper MAF-threshold 0.01/0.05, 500/500 cases/controls).