ρ
0
0.2
0.5
0.8
1
n
1
/
N
=0.3
1.96
2.023
2.108
2.182
2.225
n
1
/
N
=0.5
1.96
2.041
2.146
2.232
2.279
n
1
/
N
=0.8
1.96
2.061
2.186
2.281
2.328
Table 1:
w
0.025
for biomarker informed two-stage winner design (K=4).
