ρ 0 0.2 0.5 0.8 1
n1/N=0.3 1.96 2.048 2.165 2.27 2.33
n1/N=0.5 1.96 2.072 2.218 2.34 2.408
n1/N=0.8 1.96 2.1 2.275 2.411 2.48
Table 3: w0.025 for biomarker informed two-stage winner design (K=6).