ρ 0 0.2 0.5 0.8 1
n1/N=0.3 1.96 2.055 2.185 2.299 2.366
n1/N=0.5 1.96 2.082 2.242 2.376 2.452
n1/N=0.8 1.96 2.112 2.305 2.455 2.531
Table 4: w0.025 for biomarker informed two-stage winner design (K=7).