T1= 1

T1 = 0

 

 

T2=1

T2=0

T2=1

T2=0

Total

D=1

s11

s10

s01

s00

s

D=0

r11

r10

r01

r00

r

Total

N11

n00

n01

n00

n

Table 4: Frequencies observed when comparing two binary tests in paired designs.