Variable Difference in the Z-score 95% Confidence Interval Unadjusted p-value
CM – CC at each time point
CM – CC: baseline -0.71 (-1.08, -0.33) 0.0003
CM – CC: 3 months -0.35 (-0.73, 0.02) 0.07
CM – CC: 6 months -0.54 (-0.91, -0.16) 0.006
CM – CC: 2 years -0.58 (-0.97, -0.20) 0.003
UM – CC at each time point
UM – CC: baseline 0.24 (-0.10, 0.58) 0.17
UM – CC: 3 months 0.30 (-0.04, 0.65) 0.09
UM – CC: 6 months 0.10 (-0.25, 0.44) 0.58
UM – CC: 2 years 0.04 (-0.31, 0.39) 0.83
CM trend over time
CM: 3 months – baseline 0.24 (0.01, 0.47) 0.04
CM: 6 months – 3 months -0.08 (-0.32, 0.15) 0.48
CM: 2 years – 6 months -0.05 (-0.29, 0.20) 0.71
Table 3: Estimates of the difference in PCA-scores of cognitive tests in children with cerebral malaria (CM), uncomplicated malaria (UM) and community children (CC) from the linear mixed effects model.