OPH
Specific activity
ab
Demeton-S methyl
Malathion
VX
Wild-type OPH
-0.03x10
-5
(0.02x10
-5
)
0.14x10
-5
(0.09x10
-5
)
N/D
S308L.OPH
2.17x10
-5
(0.37x10
-5
)
2.02x10
-5
(0.10x10
-5
)
35.7x10
-5
(5.0x10
-5
)
a
μmoles hydrolyzed/min/OD600 of 1 (after correction to control cultures)
b
average of three independent cultures (standard deviation)
N/D, not determined
Table 6:
Activity of recombinant yeast cells against demeton-S methyl, malathion and VX.