Source Sum of squares Degree of freedom Mean square F-value Prob> F Remarks Model 656.43 9 72.94 16.66 < 0.0001 Significant A 6.5 1 6.5 1.48 0.2511   B 198.34 1 198.34 45.31 < 0.0001   C 277.99 1 277.99 63.5 < 0.0001   A2 9.82 1 9.82 2.24 0.1651   B2 10.45 1 10.45 2.39 0.1534   C2 13.91 1 13.91 3.18 0.105   AB 14.62 1 14.62 3.34 0.0976   AC 13.94 1 13.94 3.18 0.1047   BC 9.42 1 9.42 2.15 0.1732   Residual 43.78 10 4.38       Lack of Fit 37.6 5 7.52 6.08 0.0347 Significant Pure Error 6.18 5 1.24       Cor Total 700.21 19

Std. Dev= 2.09, Mean=89.69, C.V.= 2.33, PRESS=244.33,R-Squared=0.9375,Adj-R=0.8812 , Pred

Table 3a: Analysis of variance for response surface reduced quadratic model terms.