| Author |
Subject group |
n |
Method/BIA parameter |
Instrument |
Comments/ appreciation |
| Kim et al.
[42] |
Breast cancer-Rel |
73 |
ECF |
InBody®720 |
Estimation of ECF and SFBIA before treatment are useful screening tools for predicting the treatment outcome of patients with lymphedema. |
| Vicini et al. [76] |
Upper limb Lymphoma |
64 |
ECF |
L-Dex |
L-Dex readings paralleled the extent of surgical interventions and suggest that they can be used to monitor patients for the early onset of edema. |
| Fu et al. [77] |
symptomatic seroma |
130 |
arm swelling |
BIS |
Patients who developed symptomatic seroma had 7.78 and 10.64 times the odds of developing arm swelling and chest/breast swelling versus those who did not, respectively (p < 0.001). |
| Badalato et al. [46] |
Prostate tumor |
63 |
FFM, ECW, ICW, TBW |
ImpediMed SFB7 |
The correction of metric analysis indicated that BMI correlated with FFM (p = 0.002), FM (p = 0.01), and %TBW (p = 0.02). %FFM (p = 0.03), %FM (p = 0.03) and %TBW (p = 0.04) correlated with % tumor volume. ICW (p = 0.01) and TBW (p = 0.009) correlated with EBL. BMI (p = 0.04), %ECW (p = 0.04), FM (p = 0.05), and %ICW (p = 0.03) correlated with pathologic tumor stag.
N.P. BIA may be helpful in predicting post-surgical outcomes |
| Badalato et al. [46] |
Breast cancer |
14 |
BF |
BIA |
In this study a comparison between ADP, SKF and BIA screening was carried out. Although ADP and SKF produce similar estimates of BF percentage in all participants, BIA overestimated BF percentage relative to the other measures.
N.P. Caution is recommended when using BIA as the body composition method for breast cancer survivors who have completed treatment but are still undergoing adjuvant hormonal therapy. |
| Ward et al. [35] |
Healthy |
172 |
|
BIS |
The presence of lymphedema is indicated when the impedance ratio exceeded 1.106 when the nondominant limb is at risk, and 1.134 when the dominant limb is at risk compared with the currently used values of 1.066 and 1.139, respectively. The impedance ratio thresholds for early detection of lymphedema remain suitable for clinical use with present day bioimpedance spectroscopy analyzers. |
| Ward et al. [35] |
Healthy |
18,700 |
BMI, FFM |
BIA |
This study found some evidence for a possible relationship between higher levels of physical activity, body size and increased ovarian cancer risk. Ovarian cancer in relation to BMI was 1.22 (95% CI: 1.00, 1.48; p-trend, 0.06) per 5 kg/m(2) increment, and for fat mass, 1.23 (95% CI: 1.01, 1.49; p-trend, 0.04) per 10 kg increment. |
| Burden et al. [78] |
Colorectal cancer |
132 |
BMI, %weight loss |
BIA |
BIA screening would be beneficial at an early stage in the care pathway when they initially enter the secondary care system. |
| Liu et al. [79] |
Breast cancer. |
200 |
%BF |
BIA |
BMI and BF% were highly correlated (r=0.91; p<0.001). However, BMI exhibited poor sensitivity for identifying obesity (47%). The sensitivity of BMI to detect obesity was better in women over age 60. The best BMI cutoff for obesity was 22.3 kg/m2 with a sensitivity and specificity of 89% (95% CI=83-94%) and 87% (95% CI=77-93%) respectively, and the total accuracy rate improved from 65% to 89%.
N.P. Using BMI to identify obesity in women with breast cancer requires careful attention to the diagnostic criterion chosen. |
| Czerniec et al. [28] |
Lymphedema |
33
18 |
self-report, Perometer, the truncated cone method |
BIS |
The physical measurement tools were highly reliable (ICC((2,1)): 0.94 to 1.00) with high concordance (r(c): 0.89 to 0.99). While, Self-report correlated moderately with physical measurements (r = 0.65 to 0.71) and was moderately reliable (ICC((2,1)): 0.70). |
| Wang et al. [80] |
Breast cancer |
583 |
Techniques
sensitivities |
EIS, ultrasound |
Of the 583 cases, 143 were diagnosed with breast cancer. The sensitivities of EIS, ultrasound and the combination method were 86.7% (124/143), 72% (103/143), and 93.7% (134/143); the specificities were 72.9% (321/440), 82.5% (363/440), and 64.1% (282/440), and the relative possibilities of breast cancer for the positive young women detected by EIS, ultrasound, and the combination method were 8.67, 5.77, and 14.84, respectively.
N.P. The combination of EIS and ultrasound is an applicable method for early detection of breast cancer in young women. |
| Crawford et al. [81] |
cancer |
84 |
ECF, ICF, ECF , ICF |
BIS |
Results of this study confirm that elevated metabolic rate and accumulation of body fluid are indicators of a poor prognosis in patients with cancer receiving palliative care.
N.P. BIS allows early detection metabolic rate and accumulation of body fluid, and that it has the potential to improve prognostication. |
| Halpern-Silveira et al. [82] |
cancer |
174 |
FFM, BW |
BIA |
A significant BW change was found during the treatment in patients submitted to previous/adjuvant and palliative chemotherapy (weight gain of 4.15% and 2.23%, respectively, p = 0.05) and a significant FFM loss (7.61%, p < 0.01) in patients with severe malnutrition at admission. |
| Wallstrom et al. [83] |
Prostate cancer risk |
10,564 |
BMI |
BIA |
General adiposity, expressed as BMI or body fat percentage, and prevalent diabetes were not associated with PCa risk. |
| Isenring et al. [84] |
Oncology |
37 |
TBW |
BIS |
A cross-sectional, observational study was conducted in 37 outpatients receiving radiotherapy (27 males/10 females, aged 68.3 ± 10.2 years). In this study, TBW estimated by BIS cannot be directly compared with oncology-specific BIA equations.
N.P. BIS cannot be used at the group level in outpatients receiving radiotherapy. |
| Wu et al. [85] |
Cancer
Healthy |
936
840 |
ICF, ECF, FM, FFM |
BIA |
BIA confirmed that cancer patients exhibited lower FM and FFM |
DXA: Dual energy X-ray Absortiometry; DXA-L: Dual energy X-ray Absortiometry-Lunar; ImpediMed SFB7 Device (San Diego, CA, USA); InBody®720, (Biospace, Korea).
BIS: Bioelectrical Impedance Spectroscopy; BIA: Bioelectrical Impedance Analysis; BMI: Body Mass Index; FFM: Fat-Free Mass; BF: Body Fat; BCM: Body Cell Mass;
ECF: Extracellular Fluid; ICF; Intracellular Fluid; EBL: Estimated Blood Loss; TBW: Total Body Water; ADP: Air Displacement Plethysmography; SKF: Skinfold Thickness;
RARP: Robotic Assisted Radical Prostatectomy; Breast Cancer-Rel: Breast Cancer Related Lymphedema; UL.Lymphedema: Upper Limb Lymphedema. |
