Protein Pathway Participant Proteins Reference BER-Pathway Proteins • XRCC-1 • PARP-1 • OGG1 • pol β • DNA ligase I [48] [49] [50] [51] [52] Redox Regulation of Key TFs • NF-κB • HIF-1α • p53 • AP-1 • Pax-8 [53] [54] [9] [11] [10]

Table 1: Important APE1 Protein-Protein Interaction.