MHC-I Allele POS N SEQUENCE C MW (Da) SCORE % OPT. 8mer_H2_Db 41 DLG CAATCPTV KTG 746.89 21.518 40.99 % 8mer_H2_Db 61 STD NCNPFPTR KRP 930.05 10.742 20.46 % 8mer_H2_Db 58 QCC STDNCNPF PTR 878.91 3.74 7.12 % 8mer_H2_Db 2 I RCFITPDI TSK 946.14 0.021 0.04 % 8mer_H2_Db 14 SKD CPNGHVCY TKT 874.0 -0.041 -0.08 % 8mer_H2_Db 23 CYT KTWCDAFC SIR 932.11 -0.625 -1.19 % 8mer_H2_Db 18 PNG HVCYTKTW CDA 996.17 -4.872 -9.28 % 8mer_H2_Db 12 ITS KDCPNGHV CYT 850.94 -5.222 -9.95 % 8mer_H2_Db 13 TSK DCPNGHVC YTK 825.91 -5.524 -10.52 % 8mer_H2_Db 50 TVK TGVDIQCC STD 819.94 -6.316 -12.03 % 8mer_H2_Db 32 FCS IRGKRVDL GCA 938.14 -8.761 -16.69 % 8mer_H2_Db 22 VCY TKTWCDAF CSI 930.07 -9.103 -17.34 % 8mer_H2_Db 49 PTV KTGVDIQC CST 844.97 -9.479 -18.06 % 8mer_H2_Db 26 KTW CDAFCSIR GKR 896.06 -9.479 -18.06 % 8mer_H2_Db 62 TDN CNPFPTRK RP 944.12 -15.508 -29.54 % 8mer_H2_Db 28 WCD AFCSIRGK RVD 863.05 -18.667 -35.56 % 8mer_H2_Db 29 CDA FCSIRGKR VDL 948.16 -28.837 -54.93 %

Table 1a: Peptide binders of Alpha-Cobratoxin from N. kaouthia to MHC-I molecules, having C-terminal ends are proteosomal cleavage sites, Binding potential (score) of antigenic peptide to the MHC-1 Allele i.e. 8mer_H2_Db.