MHC-I Allele POS N SEQUENCE C MW SCORE % OPT. 9mer_H2_Db 57 IQC CSTDNCNPF PTR 982.05 14.379 28.55 % 9mer_H2_Db 12 ITS KDCPNGHVC YTK 954.08 7.581 15.05 % 9mer_H2_Db 13 TSK DCPNGHVCY TKT 989.09 5.283 10.49 % 9mer_H2_Db 40 VDL GCAATCPTV KTG 803.94 2.756 5.47 % 9mer_H2_Db 61 STD NCNPFPTRK RP 1058.22 1.882 3.74 % 9mer_H2_Db 21 HVC YTKTWCDAF CSI 1093.25 -0.651 -1.29 % 9mer_H2_Db 22 VCY TKTWCDAFC SIR 1033.21 -2.115 -4.20 % 9mer_H2_Db 25 TKT WCDAFCSIR GKR 1059.27 -2.581 -5.12 % 9mer_H2_Db 49 PTV KTGVDIQCC STD 948.11 -3.287 -6.53 % 9mer_H2_Db 31 AFC SIRGKRVDL GCA 1025.22 -6.633 -13.17 % 9mer_H2_Db 17 CPN GHVCYTKTW CDA 1053.22 -6.897 -13.69 % 9mer_H2_Db 60 CST DNCNPFPTR KRP 1045.14 -9.799 -19.46 % 9mer_H2_Db 11 DIT SKDCPNGHV CYT 938.02 -10.788 -21.42 % 9mer_H2_Db 27 TWC DAFCSIRGK RVD 978.14 -14.271 -28.34 % 9mer_H2_Db 1 - IRCFITPDI TSK 1059.3 -14.47 -28.73 % 9mer_H2_Db 48 CPT VKTGVDIQC CST 944.1 -20.758 -41.22 % 9mer_H2_Db 28 WCD AFCSIRGKR VDL 1019.24 -25.564 -50.76 %

Table 1b: Peptide binders of Alpha-Cobratoxin from N. kaouthia to MHC-I molecules, having C-terminal ends are proteosomal cleavage sites, the binding potential (score) of antigenic peptide to the MHC-1 Allele i.e. 9mer_H2_Db.