Genes Relative fold-change of genes analysed by qRT-PCR. Relative fold-change of genes analysed by microarray Spearman’s correlation test (r-value) ZRANB2 (C2) Zinc finger, RAN-binding domain containing 2 3.880 (±0.07; p=0.03) 6.33(±0.29) r=0.77 RCHY1 (C1) Ring finger 1.38(±0.21;p=0.04) 1.32 (±0.11) r=0.85 ANKFY (C1)Ankyrin 1.46(±0.54;p=0.03) 1.35(±0.11) r=0.9 ATMIN (A) ATM interactor 6.35(±0.04;p=0.01) 6.25 (±0.51) r=0.8 EFEMP1 (C1) EGF-containing fibulin-like extracellular matrix protein 1.76(±0.04;p=0.02) 1.88(±0.17) r=0.8

Table 4: Genes validated through qRT-PCR.