HD-OCT criteria BCC SCC nevus AK Fibrous Papule Sebacecous hyperplasia Pleomorphism of the epidermis (+) + - + - - Grey/dark lobular structure + - (+) - - + (granular) Peritumoural bright streaks + - - - (+) - Dark peripheral rimming + - - - - - Increased vasculature + + - + - (+) Presence of elongated monomorphic basaloid nuclei  + - - - - - Destruction of layering + + + + - -

Table 3: HD-OCT criteria in BCC (n=22) and lesions of the differential diagnosis (n=10 fibrous papules, 5 AK, 3 nevi, 2 SCC, 1 sebaceous hyperplasia).