| Features |
Familial Melanoma (N=62) |
Non Familial Melanoma (N=127) |
P |
| Phototype |
|
|
0.989 |
| -I-II |
22 (44%) |
43 (43.9%) |
|
| -III-IV |
28 (56%) |
55 (56.1%) |
|
| Hair colour |
|
|
0.138 |
| -brown/black |
36 (67.9%) |
75 (78.9%) |
|
| -blond/red |
17 (32.1%) |
20 (21.1%) |
|
| Eye colour |
|
|
0.441 |
| -dark |
31 (58.5%) |
61 (64.9%) |
|
| -fair |
22 (41.5%) |
33 (35.1%) |
|
| Nevi count |
|
|
0.021 |
| -<50 |
22 (46.8%) |
49 (68.1%) |
|
| ->50 |
25 (53.2%) |
23 (31.9%) |
|
| Elastosis |
|
|
0.086 |
| -not present |
51 (82.3%) |
89 (70.6%) |
|
| -present |
11 (17.7%) |
37 (29.4%) |
|
| Type of cells |
|
|
0.663 |
| -epithelioid |
45 (72.6%) |
101 (79.5%) |
|
| -sarcomatoid |
4 (6.5%) |
6 (4.7%) |
|
| -big round |
7 (11.3%) |
7 (5.5%) |
|
| -fusocellular |
4 (6.5%) |
9 (7.1%) |
|
| -dendritic |
2 (3.2%) |
4 (3.1%) |
|
| TIL |
|
|
0.713 |
| -not present |
10 (16.1%) |
16 (12.6%) |
|
| -mild |
45 (72.6%) |
99 (78%) |
|
| -severe |
7 (11.3%) |
12 (9.4%) |
|
| Regression |
|
|
0.236 |
| -present |
13 (21%) |
18 (14.2%) |
|
| -not present |
49 (79%) |
109 (85.8%) |
|
| Mitoses |
|
|
0.042 |
| -1 |
46 (74.2%) |
75 (59.1%) |
|
| ->1 |
16 (25.8%) |
52 (40.9%) |
|
| Pagetoid invasion |
|
|
0.976 |
| -not present |
|
|
|
| -mild |
1 (1.6%) |
2 (1.6%) |
|
| -severe |
20 (32.3%) |
39 (30.7%) |
|
| |
41 (66.1%) |
86 (67.7%) |
|
| Nests |
|
|
0.517 |
| -present |
47 (77%) |
103 (81.1%) |
|
| -not present |
14 (23%) |
24 (18.9%) |
|
| Lentiginoushyperplasia |
|
|
0.722 |
| -present |
|
|
|
| -not present |
31 (50%) |
60 (47.2%) |
|
| |
31 (50%) |
67 (52.8%) |
|
| Cellular atypia |
|
|
0.996 |
| -mild |
15 (24.2%) |
31 (24.4%) |
|
| -moderate |
31 (50%) |
64 (50.4%) |
|
| -severe |
16 (25.8%) |
32 (25.2%) |
|
| Nuclear Survivin |
|
|
0.821 |
| -positive |
13 (23.2%) |
29 (24.8%) |
|
| -negative |
43 (76.8%) |
88 (75.2%) |
|
| Cytoplasmic Survivin |
|
|
0.05 |
| -positive |
47 (83.9%) |
82 (70.1%) |
|
| -negative |
9 (16.1%) |
35 (29.9%) |
|
|
