| Features |
CDKN2A Melanoma (N=17) |
Non CDKN2A Melanoma (N=168) |
P |
| Phototype |
|
|
0.919 |
| -I-II |
6 (42.9%) |
58 (44.3%) |
|
| -III-IV |
8 (57.1%) |
73 (55.7%) |
|
| Hair colour |
|
|
0.555 |
| -brown/black |
11 (68.8%) |
97 (75.2%) |
|
| -blond/red |
5 (31.3%) |
32 (24.8%) |
|
| Eye colour |
|
|
0.833 |
| -dark |
9 (60%) |
81 (62.8%) |
|
| -fair |
6(40%) |
48 (37.2%) |
|
| Nevi count |
|
|
0.055 |
| -<50 |
5 (35.7%) |
65 (62.5%) |
|
| ->50 |
9 (64.3%) |
39 (37.5%) |
|
| Elastosis |
|
|
0.569 |
| -not present |
14 (82.4%) |
125 (74.4%) |
|
| -present |
3 (17.6%) |
43 (25.6%) |
|
| Type of cells |
|
|
0 |
| -epithelioid |
10 (58.5%) |
133 (78.7%) |
|
| -sarcomatoid |
1 (5.9%) |
9 (5.3%) |
|
| -big round |
6 (35.3%) |
8 (4.7%) |
|
| -fusocellular |
0 (0%) |
13 (7.7%) |
|
| -dendritic |
0 (0%) |
6 (3.6%) |
|
| TIL |
|
|
0.441 |
| -not present |
4 (23.5%) |
22 (13%) |
|
| -mild |
11 (64.7%) |
131 (77.5%) |
|
| -severe |
2 (11.8%) |
16 (9.5%) |
|
| Regression |
|
|
0.742 |
| -present |
2 (11.8%) |
29 (17.2%) |
|
| -not present |
15 (88.2%) |
140 (82.8%) |
|
| Mytoses |
|
|
0.242 |
| -1 |
13 (76.5%) |
105 (62.1%) |
|
| ->1 |
4 (23.5%) |
64 (37.9%) |
|
| Pagetoid invasion |
|
|
0.34 |
| -not present |
1 (5.9%) |
2 (1.2%) |
|
| -mild |
5 (29.4%) |
54 (32%) |
|
| -severe |
11 (64.7%) |
113 (66.9%) |
|
| Nests |
|
|
0.743 |
| -present |
14 (87.5%) |
134 (79.3%) |
|
| -not present |
2 (12.5%) |
35 (20.7%) |
|
| Lentiginous hyperplasia |
|
|
0.945 |
| -present |
|
|
|
| -not present |
8 (47.1%) |
81 (47.9%) |
|
| |
9 (52.9%) |
88 (52.1%) |
|
| Cellular atypia |
|
|
0.408 |
| -mild |
2 (11.8%) |
42 (24.9%) |
|
| -moderate |
9 (52.9%) |
85 (50.3%) |
|
| -severe |
6 (35.3%) |
42 (24.9%) |
|
| Nuclear Survivin |
|
|
1 |
| -positive |
4 (25%) |
38 (24.7%) |
|
| -negative |
12 (75%) |
116 (75.3%) |
|
| Cytoplasmic Survivin |
|
|
0.052 |
| -positive |
15 (93.8%) |
112 (72.7%) |
|
| -negative |
1 (6.3%) |
42 (27.3%) |
|
|
