Rating Wrinkles Skin laxity   No. of patients Percentage No. of patients Percentage Worsened 0 0 0 0 No changed 6 21 3 10 Slight (1-25%) 8 28 8 28 Moderate (26-50%) 12 30 9 31 Marked (51-75%) 6 21 9 31 Almost complete (76-90%) 0 0 0 0

Table 1: Physicians' overall ratings for the response of skin lesions