Singletreatment   Combinedtreatment p-value Note ｎ Ave.   SD   ｎ Ave.   SD -5     ｎ   %     ｎ   %     Age 11 43.9 ± 11.2   20 42.7 ± 13.2 0.7909 1 Gender Male   2   18.2     6   30 0.4634 2 Female   9   81.8     14   70 Number of areas of hair loss Average 11 2.1 ± 1.6   20 1.4 ± 0.6 0.0681 1 1   7   63.6     14   70 0.039 3 2   0   0     5   25 3   1   9.1     1   5 4   2   18.2     0   0 5   1   9.1     0   0 Area of hair loss <25％   11   100     20   100 - 2 ≥25％   0   0     0   0 Pull test                       2   11   100     20   100 - 2 3   0   0     0   0 Family history of alopecia areata Yes   2   18.2     4   20 0.9021 2 No   9   81.8     16   80 Atopicpredisposition Yes   4   36.4     4   20 0.3255 2 No   7   63.6     16   80 Lactating No   9   81.8     14   70 - 4 Pregnant No   9   81.8     14   70 - 4 History of oral steroid treatment Yes   0   0     0   0 - 2 No   11   100     20   100 Topical steroid treatment for alopecia areata Yes   0   0     1   5 0.3442 2 No   11   100     19   95 Allergy to carpronium or glycyrrhizin Yes   0   0     0   0 - 2 No   11   100     20   100 Dermatitis and eczema on scalp Yes   0   0     0   0 - 2 No   11   100     20   100 Diagnosisofmalignancy Yes   0   0     0   0 - 2 No   11   100     20   100 Severeliver,kidney,orheartdisease Yes   0   0     0   0 - 2 No   11   100     20   100 Concomitantdrug Yes   0   0     4   20 0.0505 2 No   11   100     16   80 IgE RIST   117.4 ± 156.4     218.2 ± 391.6 0.4225 1

Notes 1. Comparison between groups using Student’s t-test. 2. Comparison between groups using the χ2 test. 3. Comparison between groups using Fisher’s exact test. 4. Women only. 5. -, p-value not calculated.

Table 4: Patient characteristics.