Evaluation Singletreatment Combinedtreatment p-value n % n % Markedly improved 4 36.4 4 21.1 0.7954 Moderately improved 3 27.3 8 42.1 Slightly improved 4 36.4 5 26.3 No change 0 0 1 5.3 Worsened 0 0 1 5.3 Not determined 0 0 0 0 Total 11 100 19 100 -

Table 5: Comprehensive evaluation. Comparison between groups using Fisher’s exact test.