Figure 3: Macroscopic aspects of C57BL/6 mice bearing B16/F10 melanoma, after 20 days of treatment. Results represent means from three independent experiments. After the end of the treatment cycle, the animals were euthanized and the abdominal cavity and internal organs were macroscopically observed. Animals treated with (a) RF followed by etoposide. (b) Etoposide followed by RF. (I) Pre- euthanasia; (II) Post- euthanasia.