| Reference |
|
N |
Risk Ratio Measure |
Overall Risk Ratio (CI) |
Overall Risk Ratio (CI) of TC stratified by time since CM diagnosis |
| <10 years |
>10 years |
| Tucker et al., 1985† |
Total
M
F |
5
2
3 |
RR |
3.6*
4.8
3.1 |
<1 year
0.0
0.0
0.0 |
1-4 years
1.9
6.1
0.0 |
5-9 years
8.6*
9.8
8.1 |
>10 years
3.0
0.0
4.1 |
| Ronckers et al., 2005† |
Total |
93 |
RR |
2.01 (1.62-2.47)* |
<10 years
2.22* |
>10 years
1.53 |
| Goggins et al., 2006† |
Total
M
F |
101
39
62 |
SIR |
2.17 (1.77-2.63)*
2.49 (1.54-2.57)
2.00 (1.54-2.57) |
≤3 years
2.54 (1.78-3.51)* |
3-10 years
2.28 (1.67-3.06)* |
>10 years
1.65 (1.02-2.53)* |
| Sandeep et al., 2006† |
Total |
118 |
SIR |
1.84 (1.53-2.21)* |
<1 year
1.80 (0.93-3.14) |
1-9 years
1.64 (1.26-2.11)* |
>10 years
2.23 (1.63-2.99)* |
| Swerdlow et al., 2009 |
Total
M
F |
6
0
6 |
SIR |
1.72 (0.63-3.75)
0 .0 (0.0-5.34)
2.15 (0.79-4.68) |
|
|
|
|
| Bradford et al., 2010 |
Total |
170 |
SIR |
1.75 (1.50-2.04)* |
2 mos-1 year
5.19* |
1-5 years
1.73* |
5-10 years
1.39 |
10-20 years
1.48* |
>20 years
0.82 |
| Spanogle et al., 2010 |
Total |
217 |
SIR |
1.90 (1.65-2.17)* |
2 mos-1 year
4.06 (2.96-5.43)* |
1-5 years
2.20 (1.77-2.71)* |
5-10 years
1.37 (0.99-1.85) |
>10 years
1.40 (1.00-1.90) |
| |
|
|
|
|
|
Melanoma in situ |
|
|
| Balamurugan et al., 2011 |
M
F |
15
32 |
|
1.27
1.58* |
2 mos-1 year
--
-- |
1-5 years
1.07
1.76* |
5-10 years
1.71
1.00 |
>10 years
0.0
-- |
| |
|
SIR |
|
|
Invasive CM |
|
|
|
M
F |
54
67 |
|
2.67*
1.77* |
2 mos-1 year
7.09*
4.94* |
1-5 years
2.19*
1.25 |
5-10 years
1.12
1.16 |
>10 years
1.13
-- |
| Robsahm et al., 2014 |
M
F |
13
19 |
SIR |
2.78 (1.61-4.80)*
1.27 (0.81-1.99)* |
|
|
|
|
| Meta-Analysis |
Total
M
F |
44252
186 |
SIR |
1.88 (1.62-2.15)*
2.60 (1.65-3.55)*
1.59 (1.10-2.09)* |
|
|
|
|
| Oakley et al., 2014† |
Total |
78 |
OR |
2.3 (1.8-3.0)* |
|
|
|
|
